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Table of Contents | |
MANGANESE AND SELENIUM
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| J Lab Clin Med 1975 Jul;86(1):132-9 |
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Tissue trace element and enzyme content in pigs fed a low
manganese diet. I. A relationship between manganese and selenium.
Burch RE, Williams RV, Hahn HK, Jetton MM, Sullivan JF
Pigs received a diet containing 0.59 p.p.m. Mn. Control pigs received the
same quantity of the same diet which was supplemented with 22 p.p.m. of Mn.
At the end of 6 weeks, pigs fed the low Mn diet had a diminution in tissue
Mn levels as well as a diminution in tissue Se content. Tissue levels of Zn,
Cu, Ca, and Mg were not affected by the dietary regimen. Indicative of the
fact that experimental animals were probably Mn-deficient was a
statistically significant decrease in hepatic arginase activity that could
be enhanced by the addition of Mn. These studies represent the first
experimental evidence that there may be a specific interaction between
tissue Se and Mn. Tissue Se levels were decreased to a statistically
significant degree in all tissues studied except the kidney in the
Mn-deficient animals.
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