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BROMINE

"In the thyroid, bromine probably remained in the form of bromide and, in proportional to its increased concentration, the production of iodinated thyronines decreased, with the sum of the iodine and bromine concentrations being constant at the value of 20.51 +/- 1.16 mumol/g dry wt of the thyroid" bromine reduces iodination of thyronines.doc

"The concentration of bromine in the thyroid increased with the amount of bromine intake, while at the same time the molar ratio of iodine/bromine decreased. The plasma level of T4 was lowered after both 16 and 66 days of treatment, but the T3 level only after 66 days treatment. The level of TSH did not exhibit any significant change. The observed changes, which have a parenchymatous goitre-like character, may have a direct relevance for human medicine, since the concentrations of bromide chosen in these experiments are readily encountered in the environment." bromine effects on the thyroid.doc

"Renal cell adenomas were found as early as after 26 weeks of treatment with KBrO3. The yields of dysplastic foci, adenomas and adenocarcinomas of the kidney, follicular cell tumors of the thyroid and mesotheliomas of the peritoneum increased with treatment, the final incidences all being statistically significant after administration of KBrO3 for 104 weeks." bromine--potass.bromide induces renal and thyroid tumors.doc

 

AIMS--To examine the possible consequences of high plasma concentrations of bromine on thyroid hormone. METHODS--Bromine was measured by inductively coupled plasma mass spectrometry in the plasma of 799 patients consulting for thyroid disorders. Because the mean (SD) bromine concentration in the plasma of healthy subjects is 4 (1) mg/l, concentrations above 6 mg/l were regarded as outside the normal range. Bromine, free thyroxine (FT4), and thyroid stimulating hormone (TSH) values were compared. RESULTS--The percentage of patients with normal, low, and high FT4 and TSH plasma activities, measured separately, did not differ between patients with low and high bromine concentrations. The percentage of patients with high TSH but normal FT4 values was significantly higher in the group with bromine values of more than 6 mg/l than in the group with bromine concentrations below this (p < 0.02). CONCLUSION--An increase in plasma bromine could potentiate an increase in plasma TSH concentration, probably as a consequence of a minor inhibitory effect on thyroid activity.bromine and thyroid hormone activity.doc

The following study appears to have a typo in the title and is not about boron but about bromine (Br). Apparently the translators misunderstood the universal symbol for bromine (Br) and thought it meant boron (B). Also I don't believe boron will have these thyroid effects and most certainly bromine will, since bromine will compete with chlorine.

Vopr Kurortol Fizioter Lech Fiz Kult 1989 May-Jun;(3):28-31

[Morphofunctional characteristics of the thyroid and a change in the level of thyroid hormones in the blood from the internal use of boron-containing waters].

[Article in Russian]

Korolev IuN, Panova LN, Bobkova AS, Korovkina EG

It has been established that intake of waters identical by Br concentrations (250 mg/l) but different by an ion-salt base leads to various structural changes of the thyroid at the tissue, cellular and subcellular levels. Artificial Br-containing water induces more pronounced shifts correlating with T3 and T4, blood concentrations. The ion-salt base was found essential in the mechanism of action of Br-containing water.